Drug Detail


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Drug Name S-49076
Trade Name
Synonyms S49076
Drug Descriptions

S-49076 is a multi-kinase inhibitor that inhibits wild-type and mutant forms of MET and FGFR1-2, as well as FGFR3, AXL, MER, and AURKB, resulting in decreased downstream signaling, and potentially resulting in decreased tumor growth (PMID: 23804704, PMID: 28624695, PMID: 28619752).

DrugClasses Aurkb Inhibitors 20 AXL Inhibitor 28 FGFR1 Inhibitor 24 FGFR2 Inhibitor 18 FGFR3 Inhibitor 13 MET Inhibitor 55
CAS Registry Number 1265965-22-7


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + S-49076 Bevacizumab S-49076 0 0
S-49076 S-49076 3 0

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