Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
S-49076 is a multi-kinase inhibitor that inhibits wild-type and mutant forms of MET and FGFR1/2, as well as FGFR3, AXL, and MER, resulting in decreased downstream signaling, and potentially resulting in decreased tumor growth (PMID: 23804704).
|DrugClasses||AXL Inhibitor 27 FGFR1 Inhibitor 23 FGFR2 Inhibitor 15 FGFR3 Inhibitor 13 MET Inhibitor 55|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Bevacizumab + S-49076||Bevacizumab S-49076||1||0|