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Drug Name | AMG 458 |
Trade Name | |
Synonyms | AMG-458|AMG458 |
Drug Descriptions |
AMG 458 inhibits wild-type and mutant forms of MET and has additional activity against MST1R (RON), resulting in decreased tumor growth (PMID: 20015007, PMID: 22836051). |
DrugClasses | MET Inhibitor 59 RON Inhibitor 11 |
CAS Registry Number | 913376-83-7 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AMG 458 | AMG 458 | 0 | 0 |