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Drug Name Serdemetan
Trade Name
Synonyms JNJ-26854165|JNJ 26854165
Drug Descriptions

Serdemetan (JNJ-26854165) is a small molecule that regulates ABCA1 expression and inhibits cholesterol transport, resulting in activation of p53 and increased cell death in Tp53 wild-type and mutant cells (PMID: 23820125, PMID: 27999193).

DrugClasses p53 Activator 11
CAS Registry Number 881202-45-5
NCIT ID C77904


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Imatinib + Serdemetan Imatinib Serdemetan 0 0
PD180970 + Serdemetan PD180970 Serdemetan 0 0
Serdemetan Serdemetan 2 0

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