Drug Detail

Drug Name Serdemetan
Trade Name
Synonyms JNJ-26854165
Drug Descriptions

Serdemetan (JNJ-26854165) is a small molecule that regulates ABCA1 expression and inhibits cholesterol transport, resulting in activation of p53 and increased cell death in p53 wild-type and mutant cells (PMID: 23820125).

DrugClasses p53 Activator 9

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Imatinib + Serdemetan Imatinib Serdemetan 0 0
PD180970 + Serdemetan PD180970 Serdemetan 0 0
Serdemetan Serdemetan 2 0


Additional content available in CKB BOOST