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Drug Name Itacitinib
Trade Name
Synonyms INCB039110|INCB-039110|INCB 039110
Drug Descriptions

Itacitinib (INCB039110) is a selective inhibitor of Janus kinase 1 (JAK1), which may inhibit cell proliferation (PMID: 25605813, PMID: 32861662).

DrugClasses JAK1 Inhibitor 9

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Alemtuzumab + Itacitinib Alemtuzumab Itacitinib 0 1
Dabrafenib + Itacitinib + Trametinib Dabrafenib Itacitinib Trametinib 0 1
Dezapelisib + Itacitinib Dezapelisib Itacitinib 1 1
Epacadostat + Itacitinib Epacadostat Itacitinib 0 1
Everolimus + Itacitinib Everolimus Itacitinib 0 1
Gemcitabine + Itacitinib + Nab-paclitaxel Gemcitabine Itacitinib Nab-paclitaxel 1 0
Ibrutinib + Itacitinib Ibrutinib Itacitinib 0 1
INCB054329 + Itacitinib INCB054329 Itacitinib 1 0
Itacitinib Itacitinib 0 6
Itacitinib + Osimertinib Itacitinib Osimertinib 0 1
Itacitinib + Parsaclisib Itacitinib Parsaclisib 1 3
Itacitinib + Pembrolizumab Itacitinib Pembrolizumab 0 2
Itacitinib + Ruxolitinib Itacitinib Ruxolitinib 0 1


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