Drug Detail

Drug Name Galunisertib
Trade Name
Synonyms LY2157299
Drug Descriptions

Galunisertib (LY2157299) is a TGFBR1 antagonist, which inhibits downstream signaling and may suppress tumor growth (PMID: 18039567).

DrugClasses TGFBR1 inhibitor 12

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Galunisertib Abemaciclib Galunisertib 0 1
Capecitabine + Galunisertib Capecitabine Galunisertib 0 1
Carboplatin + Galunisertib + Paclitaxel Carboplatin Galunisertib Paclitaxel 0 1
Durvalumab + Galunisertib Durvalumab Galunisertib 0 1
Fluorouracil + Galunisertib Fluorouracil Galunisertib 0 1
Galunisertib Galunisertib 1 6
Galunisertib + Paclitaxel Galunisertib Paclitaxel 0 1
Galunisertib + Sorafenib Galunisertib Sorafenib 0 1


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