Drug Detail


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Drug Name Birinapant
Trade Name
Synonyms TL32711
Drug Descriptions

TL32711 (birinapant) is a a bivalent SMAC-mimetic compound, which binds to and inhibits Inhibitor of Apoptosis proteins (IAPs), leading to tumor cell death (PMID: 24563541, PMID: 26566079).

DrugClasses SMAC Mimetic 8
CAS Registry Number 1260251-31-7
NCIT ID C88295


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Birinapant Birinapant 1 2
Birinapant + Pembrolizumab Birinapant Pembrolizumab 0 1
Birinapant + Radiotherapy Birinapant Radiotherapy 0 0

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