Drug Detail


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Drug Name Milciclib
Trade Name
Synonyms PHA-848125AC|PHA-848125|PHA 848125
Drug Descriptions

Milciclib (PHA-848125AC) is a TRKA inhibitor with additional activity against CDK1, CDK2, CDK4, CDK5, and CDK7, potentially resulting in decreased tumor cell growth (PMID: 22160853, PMID: 28424962).

DrugClasses CDK1 Inhibitor 13 CDK2 Inhibitor 25 CDK4 Inhibitor 16 CDK5 Inhibitor 8 CDK7 Inhibitor 15 TrkA Receptor Inhibitor 8
CAS Registry Number 802539-81-7
NCIT ID C148410


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Gemcitabine + Milciclib Gemcitabine Milciclib 0 0
Milciclib Milciclib 1 2

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