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Drug Name VX-11e
Trade Name
Synonyms VX11e|VX 11e
Drug Descriptions

VX-11e is an ATP-competitive inhibitor of Mapk1 (Erk2) and Mapk3 (Erk1), which may result in growth inhibition and tumor regression (PMID: 17300186, PMID: 19827834, PMID: 31482470).

DrugClasses ERK Inhibitor (pan) 15

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Fulvestrant + VX-11e Fulvestrant VX-11e 0 0
Venetoclax + VX-11e VX-11e Venetoclax 1 0
VX-11e VX-11e 2 0
VX-11e + WEHI-539 VX-11e WEHI-539 1 0


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