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MK-4166 is an activating monoclonal antibody against the glucocorticoid-induced tumor necrosis factor receptor, TNFRSF18 (GITR, CD357), which leads to enhanced cytotoxic immune response against tumor cells (PMID: 28611044).
|DrugClasses||GITR Antibody 6|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|MK-4166 + Nivolumab||MK-4166 Nivolumab||0||1|