Drug Detail


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Drug Name MK-4166
Trade Name
Synonyms MK4166|MK 4166
Drug Descriptions

MK-4166 is an activating monoclonal antibody against the glucocorticoid-induced tumor necrosis factor receptor, TNFRSF18 (GITR, CD357), which leads to enhanced cytotoxic immune response against tumor cells (PMID: 28611044).

DrugClasses GITR Antibody 6
CAS Registry Number NA
NCIT ID C116065


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Therapy Name Drugs Efficacy Evidence Clinical Trials
MK-4166 MK-4166 0 1
MK-4166 + Nivolumab MK-4166 Nivolumab 0 1
MK-4166 + Pembrolizumab MK-4166 Pembrolizumab 0 0

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