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Drug Name Ieramilimab
Trade Name
Synonyms LAG-525|LAG525|IMP-701
Drug Descriptions

Ieramilimab (LAG525) is a monoclonal antibody that targets LAG3 and blocks interaction with MHC class II molecules, leading to enhanced T-cell response to tumor cells and decreased tumor growth (NCI Drug Dictionary).

DrugClasses Immune Checkpoint Inhibitor 148 LAG3 Antibody 17
CAS Registry Number 2137049-37-5
NCIT ID C122683

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Canakinumab + Ieramilimab + Spartalizumab Canakinumab Ieramilimab Spartalizumab 0 1
Capmatinib + Ieramilimab + Spartalizumab Capmatinib Ieramilimab Spartalizumab 0 1
Carboplatin + Ieramilimab Carboplatin Ieramilimab 0 1
Carboplatin + Ieramilimab + Spartalizumab Carboplatin Ieramilimab Spartalizumab 0 1
Ieramilimab Ieramilimab 0 2
Ieramilimab + MCS110 + Spartalizumab Ieramilimab MCS110 Spartalizumab 0 1
Ieramilimab + PBF-509 + Spartalizumab Ieramilimab PBF-509 Spartalizumab 0 1
Ieramilimab + Spartalizumab Ieramilimab Spartalizumab 0 2


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