Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Ieramilimab
Trade Name
Synonyms LAG-525|LAG525|IMP-701
Drug Descriptions

Ieramilimab (LAG525) is a monoclonal antibody that targets LAG3 and blocks interaction with MHC class II molecules, leading to enhanced T-cell response to tumor cells and decreased tumor growth (NCI Drug Dictionary).

DrugClasses Immune Checkpoint Inhibitor 148 LAG3 Antibody 18
CAS Registry Number 2137049-37-5
NCIT ID C122683


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Canakinumab + Ieramilimab + Spartalizumab Canakinumab Ieramilimab Spartalizumab 0 1
Capmatinib + Ieramilimab + Spartalizumab Capmatinib Ieramilimab Spartalizumab 0 1
Carboplatin + Ieramilimab Carboplatin Ieramilimab 0 1
Carboplatin + Ieramilimab + Spartalizumab Carboplatin Ieramilimab Spartalizumab 0 1
Ieramilimab Ieramilimab 0 2
Ieramilimab + MCS110 + Spartalizumab Ieramilimab MCS110 Spartalizumab 0 1
Ieramilimab + Spartalizumab Ieramilimab Spartalizumab 0 2
Ieramilimab + Spartalizumab + Taminadenant Ieramilimab Spartalizumab Taminadenant 0 1

Additional content available in CKB BOOST