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Drug Name LAG525
Trade Name
Synonyms LAG-525|Leramilimab
Drug Descriptions

LAG525 (Leramilimab) is a monoclonal antibody that targets LAG3 and blocks interaction with MHC class II molecules, leading to enhanced T-cell response to tumor cells and decreased tumor growth (NCI Drug Dictionary).

DrugClasses Immune Checkpoint Inhibitor 98 LAG3 Antibody 12
CAS Registry Number 2137049-37-5
NCIT ID C122683

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Canakinumab + LAG525 + Spartalizumab Canakinumab LAG525 Spartalizumab 0 1
Capmatinib + LAG525 + Spartalizumab Capmatinib LAG525 Spartalizumab 0 1
Carboplatin + LAG525 Carboplatin LAG525 0 1
Carboplatin + LAG525 + Spartalizumab Carboplatin LAG525 Spartalizumab 0 1
LAG525 LAG525 0 2
LAG525 + MCS110 + Spartalizumab LAG525 MCS110 Spartalizumab 0 1
LAG525 + PBF-509 + Spartalizumab LAG525 PBF-509 Spartalizumab 0 1
LAG525 + Spartalizumab LAG525 Spartalizumab 0 2


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