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Drug Name Derazantinib
Trade Name
Synonyms ARQ 087
Drug Descriptions

Derazantinib (ARQ 087) is an ATP-competitive multi-kinase inhibitor with activity against Fgfr 1/2, FGFR fusions, Arg, Lck, and Kit, which prevents cell proliferation and angiogenesis (PMID: 27627808).

DrugClasses FGFR1 Inhibitor 28 FGFR2 Inhibitor 22 KIT Inhibitor 57 LCK Inhibitor 6
CAS Registry Number 1234356-69-4
NCIT ID C104267

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Derazantinib Atezolizumab Derazantinib 0 3
Derazantinib Derazantinib 15 4
Derazantinib + Paclitaxel + Ramucirumab Derazantinib Paclitaxel Ramucirumab 0 1


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