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Drug Name PTC299
Trade Name
Synonyms CS-0087039
Drug Descriptions

PTC299 inhibits dihydroorotate dehydrogenase (DHODH), thereby preventing pyrimidine nucleotide synthesis, potentially resulting in decreased MYC expression and VEGFA production, and reduced tumor cell migration and proliferation (PMID: 30352802, PMID: 33496740).

DrugClasses
CAS Registry Number 1219951-09-3
NCIT ID C91100

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Therapy Name Drugs Efficacy Evidence Clinical Trials
PTC299 PTC299 0 1


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