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CPI-169 inhibits EZH2, resulting in reduced H3K27 tri-methylation, and potentially leading to decreased tumor cell proliferation and reduced tumor growth (PMID: 25457180).
|DrugClasses||EZH2 inhibitor 18|
|CAS Registry Number||1450655-76-1|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|CPI-169 + RN-1||CPI-169 RN-1||0||0|