Drug Detail


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Drug Name PD173074
Trade Name
Synonyms PD-173074|PD 173074
Drug Descriptions

PD173074 is an ATP-competitive inhibitor of FGFR1, FGFR3, FGFR4, and KDR (VEGFR2), which may reduce proliferation and induce apoptosis in cancer cells (PMID: 9774334, PMID: 24126887, PMID: 14715624, PMID: 30544798).

DrugClasses FGFR1 Inhibitor 26 FGFR3 Inhibitor 17 FGFR4 Inhibitor 8 VEGFR2 Inhibitor 36
CAS Registry Number 219580-11-7


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABT-737 + PD173074 ABT-737 PD173074 3 0
Fulvestrant + Palbociclib + PD173074 Fulvestrant PD173074 Palbociclib 0 0
Fulvestrant + PD173074 Fulvestrant PD173074 0 0
Gefitinib + PD173074 Gefitinib PD173074 0 0
Palbociclib + PD173074 PD173074 Palbociclib 0 0
PD173074 PD173074 32 0
PD173074 + Quizartinib PD173074 Quizartinib 0 0
PD173074 + Trabectedin PD173074 Trabectedin 1 0

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