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Drug Name MEDI0680
Trade Name
Synonyms AMP-514|AMP514|MEDI-0680
Drug Descriptions

MEDI0680 (AMP-514) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 31439037).

DrugClasses Immune Checkpoint Inhibitor 98 PD-L1/PD-1 antibody 67
CAS Registry Number NA
NCIT ID C113332

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Durvalumab + MEDI0680 Durvalumab MEDI0680 0 1
MEDI0680 MEDI0680 1 1


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