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Drug Name TAK-632
Trade Name
Synonyms TAK 632|TAK632
Drug Descriptions

TAK-632 is an inhibitor of Raf, which has been shown to suppress the kinase activity of the Raf dimer thereby resulting in diminished paradoxical activation of Raf (PMID: 24121489, PMID: 31734178).

DrugClasses RAF Inhibitor (Pan) 23
CAS Registry Number 1228591-30-7


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bosutinib + TAK-632 Bosutinib TAK-632 0 0
Osimertinib + TAK-632 Osimertinib TAK-632 0 0
PLX4720 + TAK-632 PLX4720 TAK-632 1 0
Saracatinib + TAK-632 Saracatinib TAK-632 0 0
TAK-632 TAK-632 13 0

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