Drug Detail

Drug Name NSC59984
Trade Name
Drug Descriptions

NSC59984 is a small molecule that both induces degradation of mutant Tp53 and reactivates Tp53 pathway signaling through Tp73, which may result in increased cell death in Tp53-mutant tumor cells (PMID: 26294215).

DrugClasses p53 Activator 9


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cisplatin + NSC59984 Cisplatin NSC59984 1 0
NSC59984 NSC59984 4 0

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