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Drug Name GS-493
Trade Name
Synonyms GS493|GS 493
Drug Descriptions

GS-493 is a catalytic-site inhibitor of Shp2, which may result in decreased cell growth and inhibition of tumor growth (PMID: 25877780).

DrugClasses SHP2 Inhibitor 20
CAS Registry Number 1710337-31-7


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Therapy Name Drugs Efficacy Evidence Clinical Trials
GS-493 GS-493 0 0
GS-493 + Selumetinib GS-493 Selumetinib 0 0
GS-493 + Trametinib GS-493 Trametinib 0 0

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