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Drug Name APTO-253
Trade Name
Synonyms LOR-253|LT-253
Drug Descriptions

APTO-253 is a small molecule that induces expression of KLF4 and CDKN1A, resulting in decreased tumor cell proliferation, cell-cycle arrest, and apoptosis, and has been shown to induce DNA damage (PMID: 26268924, PMID: 29626127, PMID: 29626126).

DrugClasses
CAS Registry Number 1422731-37-0
NCIT ID C95724

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Therapy Name Drugs Efficacy Evidence Clinical Trials
APTO-253 APTO-253 0 1


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