Drug Detail


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Drug Name SGI-1776
Trade Name
Drug Descriptions

SGI-1776 is a small molecule inhibitor of PIMs 1, 2, 3, and FLT-3, which may result in cell death via indirect inhibition of Mcl-1 transcription and protein synthesis (PMID: 21628411, PMID: 32558942).

DrugClasses PIM Inhibitor (Pan) 9
CAS Registry Number 1025065-69-3
NCIT ID C82404


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Palbociclib + SGI-1776 Palbociclib SGI-1776 1 0
Ruxolitinib + SGI-1776 Ruxolitinib SGI-1776 1 0
SGI-1776 SGI-1776 1 0

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