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Drug Name Sabatolimab
Trade Name
Synonyms MBG453|MBG-453|MBG 453
Drug Descriptions

Sabatolimab (MBG453) is monoclonal antibody that targets T-cell immunoglobulin and mucin domain-3 protein (TIM-3, HAVCR2), potentially resulting in enhanced anti-tumor immune response (PMID: 29544515, PMID: 31847708).

DrugClasses Immune Checkpoint Inhibitor 148 TIM-3 Antibody 8
CAS Registry Number 2252262-24-9
NCIT ID C124850

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Azacitidine + Decitabine + Sabatolimab Azacitidine Decitabine Sabatolimab 0 1
Azacitidine + Decitabine and Cedazuridine + Sabatolimab Azacitidine Decitabine and Cedazuridine Sabatolimab 0 1
Azacitidine + Sabatolimab Azacitidine Sabatolimab 0 3
Azacitidine + Sabatolimab + Venetoclax Azacitidine Sabatolimab Venetoclax 0 2
Canakinumab + Sabatolimab Canakinumab Sabatolimab 0 1
Decitabine + Sabatolimab Decitabine Sabatolimab 0 2
Decitabine + Sabatolimab + Spartalizumab Decitabine Sabatolimab Spartalizumab 0 1
NIS793 + Sabatolimab NIS793 Sabatolimab 0 1
Sabatolimab Sabatolimab 0 4
Sabatolimab + Siremadlin Sabatolimab Siremadlin 0 1
Sabatolimab + Spartalizumab Sabatolimab Spartalizumab 0 1


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