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Drug Name Tetrahydrouridine
Trade Name
Synonyms THU
Drug Descriptions

Tetrahydrouridine is a synthetic pyrimidine analogue that inhibits deoxycytidine monophosphate (dCMP) deaminase, which in turn inhibits cell proliferation (PMID: 22616006, PMID: 32314030).

DrugClasses
CAS Registry Number 18771-50-1
NCIT ID C868

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Therapy Name Drugs Efficacy Evidence Clinical Trials
5-Fluoro-2-deoxycytidine + Tetrahydrouridine 5-Fluoro-2-deoxycytidine Tetrahydrouridine 0 2
Celecoxib + Decitabine + Tetrahydrouridine Celecoxib Decitabine Tetrahydrouridine 0 1
Decitabine + Nivolumab + Tetrahydrouridine Decitabine Nivolumab Tetrahydrouridine 0 1
Decitabine + Pembrolizumab + Tetrahydrouridine Decitabine Pembrolizumab Tetrahydrouridine 0 0
Decitabine + Tetrahydrouridine Decitabine Tetrahydrouridine 0 3
Tetrahydrouridine Tetrahydrouridine 0 0


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