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Drug Name PF-573228
Trade Name
Synonyms PF-573,228|PF573228|PF 573228
Drug Descriptions

PF-573228 is a small molecule inhibitor of PTK2 (FAK), which may reduce cell migration and decrease focal adhesion cellular turnover, thus suppressing metastasis (PMID: 17395594, PMID: 30352800, PMID: 32349327).

DrugClasses FAK inhibitor 13
CAS Registry Number 869288-64-2


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bosutinib + Osimertinib + PF-573228 Bosutinib Osimertinib PF-573228 0 0
Gefitinib + PF-573228 Gefitinib PF-573228 0 0
Lexatumumab + PF-573228 Lexatumumab PF-573228 0 0
Osimertinib + PF-573228 + Saracatinib Osimertinib PF-573228 Saracatinib 0 0
PF-573228 PF-573228 0 0

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