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Drug Name F14512
Trade Name
Synonyms F-14512
Drug Descriptions

F14512 is composed of a derivative of the topoisomerase II inhibitor etoposide linked to a spermidine chain, which enables cellular uptake through the polyamine transport system, resulting in increased DNA damage and decreased tumor growth (PMID: 19047165, PMID: 30547316).

DrugClasses TOPO2 inhibitor 5
CAS Registry Number 866874-63-7
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
F14512 F14512 0 0


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