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Drug Name | F14512 |
Trade Name | |
Synonyms | F-14512 |
Drug Descriptions |
F14512 is composed of a derivative of the topoisomerase II inhibitor etoposide linked to a spermidine chain, which enables cellular uptake through the polyamine transport system, resulting in increased DNA damage and decreased tumor growth (PMID: 19047165, PMID: 30547316). |
DrugClasses | TOPO2 inhibitor 5 |
CAS Registry Number | 866874-63-7 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
F14512 | F14512 | 0 | 0 |