Drug Detail


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Drug Name Tavolimab
Trade Name
Synonyms MEDI0562|MEDI-0562|Tavolixizumab
Drug Descriptions

Tavolimab (MEDI0562) is an activating monoclonal antibody to TNFRSF4 (OX40, CD134), which mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance an anti-tumor response (Annals of Oncology, Volume 27, Issue suppl_6, 1 October 2016, 1052PD).

DrugClasses OX40 Antibody 12
CAS Registry Number 1635395-25-3
NCIT ID C120041


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Durvalumab + Tavolimab Durvalumab Tavolimab 0 1
Tavolimab Tavolimab 0 2
Tavolimab + Tremelimumab Tavolimab Tremelimumab 0 2

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