Drug Detail


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Drug Name Tebentafusp
Trade Name Kimmtrak
Synonyms ImmTAC-gp100|Tebentafusp-tebn|IMCgp100
Drug Descriptions

Kimmtrak (tebentafusp) is a gp100 antigen-specific human T-cell receptor (TCR) linked to an anti-CD3 antibody fragment, which activates cytotoxic immune response against gp100-expressing tumor cells (PMID: 24531387, PMID: 31336704, PMID: 32816891). Kimmtrak (tebentafusp) is FDA approved for use in HLA-A*2:01-positive metastatic or unresectable uveal melanoma patients.

CAS Registry Number 1874157-95-5
NCIT ID C94208


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + Tebentafusp Pembrolizumab Tebentafusp 0 1
Tebentafusp Tebentafusp 0 6

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