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GNE-317 is a dual PI3K/mTOR inhibitor that crosses the blood-brain barrier, resulting in decreased downstream signaling and potentially leading to reduced growth of tumors, including brain tumors (PMID: 22992516, PMID: 28493046).
|DrugClasses||mTOR Inhibitor 51 PI3K Inhibitor (Pan) 38|
|CAS Registry Number||1394076-92-6|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|