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Drug Name CTX-1
Trade Name
Synonyms CTX1
Drug Descriptions

CTX-1 binds to and inhibits Mdm4 (MdmX), which disrupts the interaction between Tp53 and Mdm4, leading to stabilization of Tp53 and potentially leading to increased tumor cell death (PMID: 26883273).

DrugClasses MDM4 inhibitor 8
CAS Registry Number 501935-96-2


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Therapy Name Drugs Efficacy Evidence Clinical Trials
CTX-1 CTX-1 4 0
CTX-1 + Nutlin-3a CTX-1 Nutlin-3a 2 0

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