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Drug Name | CGP57380 |
Trade Name | |
Synonyms | CGP-57380|CGP 57380 |
Drug Descriptions |
CGP57380 inhibits MAPK-interacting protein kinase (MNK) 1 and 2, and may have additional activity against other protein kinases, leading to decreased phosphorylation of eIF4E and potentially resulting in decreased tumor cell growth and migration (PMID: 17850214, PMID: 21406405, PMID: 26609108, PMID: 30297804). |
DrugClasses | MNK1/2 Inhibitor 3 |
CAS Registry Number | 522629-08-9 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CGP57380 | CGP57380 | 0 | 0 |