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Drug Name rAd-hCD40L
Trade Name
Synonyms rAd.CD40L|ISF35
Drug Descriptions

rAd-hCD40L is a recombinant adenovirus vector expressing human CD40LG (CD40L), which activates TNFRSF5 (CD40) signaling and leads to apoptosis and growth inhibition in tumor cells (PMID: 19461675).

DrugClasses
CAS Registry Number NA
NCIT ID C2493

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + rAd-hCD40L Pembrolizumab rAd-hCD40L 0 1
rAd-hCD40L rAd-hCD40L 0 0


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