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Drug Name G1T38
Trade Name
Synonyms Lerociclib
Drug Descriptions

Lerociclib (G1T38) is a selective CDK4/6 inhibitor, which results in cell cycle arrest and tumor cell death (PMID: 32130619).

DrugClasses CDK4/6 Inhibitor 11
CAS Registry Number 1628256-23-4
NCIT ID C138165

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Enzalutamide + G1T38 Enzalutamide G1T38 0 0
Fulvestrant + G1T38 Fulvestrant G1T38 0 1
G1T38 G1T38 0 0
G1T38 + G1T48 G1T38 G1T48 0 0
G1T38 + Letrozole G1T38 Letrozole 0 1
G1T38 + Osimertinib G1T38 Osimertinib 0 1


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