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| Drug Name | Enfortumab vedotin-ejfv |
| Trade Name | Padcev |
| Synonyms | AGS-22ME|Enfortumab vedotin|AGS-22M6E|ASG-22CE |
| Drug Descriptions |
Padcev (enfortumab vedotin-ejfv) is an antibody-drug conjugate (ADC) that fuses together a human antibody against NECTIN4 and monomethyl auristatin E, which may result in inhibition of tumor growth and tumor regression (PMID: 27013195). Padcev (enfortumab vedotin-ejfv) is FDA approved for use in patients with locally advanced or metastatic urothelial cancer who have previously received a PD-1 or PD-L1 inhibitor, and a platinum-containing chemotherapy, or who are ineligible for cisplatin-containing chemotherapy and have previously received one or more prior lines of therapy, and in combination with Keytruda (pembrolizumab) for patients with locally advanced or metastatic urothelial carcinoma ineligible for cisplatin-containing chemotherapy (FDA.gov). |
| DrugClasses | |
| CAS Registry Number | 1346452-25-2 |
| NCIT ID | C114500 |
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