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Drug Name | Enfortumab vedotin-ejfv |
Trade Name | Padcev |
Synonyms | AGS-22ME|Enfortumab vedotin|AGS-22M6E|ASG-22CE |
Drug Descriptions |
Padcev (enfortumab vedotin-ejfv) is an antibody-drug conjugate (ADC) that fuses together a human antibody against NECTIN4 and monomethyl auristatin E, which may result in inhibition of tumor growth and tumor regression (PMID: 27013195). Padcev (enfortumab vedotin-ejfv) is FDA approved for use in patients with locally advanced or metastatic urothelial cancer who have previously received a PD-1 or PD-L1 inhibitor, and a platinum-containing chemotherapy, or who are ineligible for cisplatin-containing chemotherapy and have previously received one or more prior lines of therapy (FDA.gov). |
DrugClasses | |
CAS Registry Number | 1346452-25-2 |
NCIT ID | C114500 |