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UM-164 is a small molecule that binds to a specific inactive conformation of Src, resulting in inhibition of Src downstream signaling and inhibits p38 MAPKs, resulting in growth inhibition, and apoptosis in tumor cells (PMID: 27154914, PMID: 29282631, PMID: 28463369).
|DrugClasses||p38 MAPK Inhibitor (Pan) 4 SRC Inhibitor 30|
|CAS Registry Number||903564-48-7|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|