Drug Detail


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Drug Name INCAGN01876
Trade Name
Synonyms INCAGN1876|INCAGN-1876|INCAGN 1876
Drug Descriptions

INCAGN01876 is an activating monoclonal antibody that binds to the glucocorticoid-induced tumor necrosis factor receptor, TNFRSF18 (GITR, CD357), which leads to activation of GITR and potentially results in activation of anti-tumor immunity (NCI Drug Dictionary).

DrugClasses GITR Antibody 6
CAS Registry Number 2207590-51-8
NCIT ID C126643


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Therapy Name Drugs Efficacy Evidence Clinical Trials
DPV-001 + INCAGN01876 + Retifanlimab DPV-001 INCAGN01876 Retifanlimab 0 1
Epacadostat + INCAGN01876 + Pembrolizumab Epacadostat INCAGN01876 Pembrolizumab 0 1
INCAGN01876 INCAGN01876 0 1
INCAGN01876 + Ipilimumab INCAGN01876 Ipilimumab 0 1
INCAGN01876 + Ipilimumab + Nivolumab INCAGN01876 Ipilimumab Nivolumab 0 1
INCAGN01876 + Nivolumab INCAGN01876 Nivolumab 0 1
INCAGN01876 + Retifanlimab INCAGN01876 Retifanlimab 0 2

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