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BPR1J373 is a derivative of 5-phenylthiazol-2-ylamine-pyriminide that inhibits multiple tyrosine kinases including KIT, FLT3, VEGFR1, 2, 3, PDGFR-alpha, PDGFR-beta, RET, and SRC, and may result in anti-tumor activity (PMID: 27512117, PMID: 30142229).
|DrugClasses||FLT3 Inhibitor 62 KIT Inhibitor 56 PDGFR Inhibitor (Pan) 28 RET Inhibitor 50 SRC Inhibitor 31 VEGFR Inhibitor (Pan) 35|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|