Drug Detail


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Drug Name E7107
Trade Name
Synonyms E 7107|E-7107
Drug Descriptions

E7107 is a derivative of Pladienolide D, which inhibits assembly of the spliceosome specifically by binding to SF3B1, thereby inhibiting splicing of pre-mRNA and cell-cycle progression (PMID: 27622333, PMID: 31558432).

CAS Registry Number 630100-90-2
NCIT ID C69005


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Therapy Name Drugs Efficacy Evidence Clinical Trials
E7107 E7107 0 0
E7107 + GSK3203591 E7107 GSK3203591 0 0
E7107 + GSK3203591 + MS023 E7107 GSK3203591 MS023 0 0
E7107 + MS023 E7107 MS023 0 0

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