Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name NHS-IL12
Trade Name
Synonyms M9241|M-9241
Drug Descriptions

NHS-IL12 (M9241) is an immunocytokine composed of IL-12 linked to human tumor necrosis factor targeted IgG1, which may result in enhanced anti-tumor immune response (PMID: 24681847).

DrugClasses
CAS Registry Number 1807503-77-0
NCIT ID C97961

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
ALT-803 + Bintrafusp alfa + CV301 + NHS-IL12 ALT-803 Bintrafusp alfa CV301 NHS-IL12 0 1
Avelumab + NHS-IL12 Avelumab NHS-IL12 0 1
Bintrafusp alfa + Degarelix + Docetaxel + NHS-IL12 + Prednisone Bintrafusp alfa Degarelix Docetaxel NHS-IL12 Prednisone 0 1
Bintrafusp alfa + Docetaxel + NHS-IL12 Bintrafusp alfa Docetaxel NHS-IL12 0 1
Bintrafusp alfa + Entinostat + NHS-IL12 Bintrafusp alfa Entinostat NHS-IL12 0 1
Bintrafusp alfa + NHS-IL12 Bintrafusp alfa NHS-IL12 0 4
Bintrafusp alfa + NHS-IL12 + PDS0101 Bintrafusp alfa NHS-IL12 PDS0101 0 1
Degarelix + Docetaxel + NHS-IL12 + Prednisone Degarelix Docetaxel NHS-IL12 Prednisone 0 1
Docetaxel + NHS-IL12 Docetaxel NHS-IL12 0 1
Docetaxel + NHS-IL12 + Prednisone Docetaxel NHS-IL12 Prednisone 0 0
Entinostat + NHS-IL12 Entinostat NHS-IL12 0 1
Enzalutamide + NHS-IL12 Enzalutamide NHS-IL12 0 1
Fluorouracil + Irinotecan + Leucovorin + NHS-IL12 Fluorouracil Irinotecan Leucovorin NHS-IL12 0 1
Fluorouracil + Leucovorin + NHS-IL12 + Oxaliplatin Fluorouracil Leucovorin NHS-IL12 Oxaliplatin 0 1
Irinotecan + Leucovorin + NHS-IL12 Irinotecan Leucovorin NHS-IL12 0 0
NHS-IL12 NHS-IL12 0 3


Additional content available in CKB BOOST