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IRAK1/4 is an inhibitor of interleukin-1 receptor associated kinases 1 and 4, which results in stabilization of wild-type KMT2A, thereby potentially leading to inhibition of cell growth and delayed disease progression in KMT2A fusion specific cancers (PMID: 28065413, PMID: 32489949).
|DrugClasses||IRAK1/4 Inhibitor 1|
|CAS Registry Number||509093-47-4|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|