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Drug Name Ulevostinag
Trade Name
Synonyms MK 1454|MK-1454
Drug Descriptions

Ulevostinag (MK-1454) is an agonist of the stimulator of interferon genes protein (TMEM173, STING1), that when activated leads to the release of cytokines that stimulate cytotoxic T lymphocytes to enhance the anti-tumor immune response (Ann Oncol, Oct 2018, 29 (suppl 8), abstract LBA15, PMID: 31355488).

DrugClasses STING1 Agonist 19
CAS Registry Number NA
NCIT ID C132258

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + Ulevostinag Pembrolizumab Ulevostinag 0 2
Ulevostinag Ulevostinag 0 1


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