Drug Detail


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Drug Name NVP-TNKS656
Trade Name
Synonyms NVP656
Drug Descriptions

NVP-TNKS656 is a small molecule that inhibits Tankyrase, resulting in decreased Beta-catenin signaling, and potentially leading to reduced tumor growth (PMID: 26224873, PMID: 30944457, PMID: 31897238).

DrugClasses Tankyrase Inhibitor 10
CAS Registry Number 1419949-20-4


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Therapy Name Drugs Efficacy Evidence Clinical Trials
NVP-TNKS656 + Selumetinib NVP-TNKS656 Selumetinib 1 0
NVP-TNKS656 + Trametinib NVP-TNKS656 Trametinib 4 0
NVP-TNKS656 + Triciribine NVP-TNKS656 Triciribine 1 0

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