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Drug Name BETd-246
Trade Name
Synonyms BET-d246
Drug Descriptions

BETd-246 is a small molecule that induces degradation of Brd2, Brd3, and Brd4 proteins, leading to apoptosis of tumor cells (PMID: 28209615, PMID: 30797188).

DrugClasses BRD2 Inhibitor 1 BRD3 Inhibitor 2 BRD4 Inhibitor 9
CAS Registry Number 2140289-17-2


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Therapy Name Drugs Efficacy Evidence Clinical Trials
A-1155463 + BETd-246 A-1155463 BETd-246 0 0
BETd-246 BETd-246 0 0
BETd-246 + BM-1197 BETd-246 BM-1197 0 0
BETd-246 + Navitoclax BETd-246 Navitoclax 0 0

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