Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name NIS793
Trade Name
Synonyms nisevokitug
Drug Descriptions

NIS793 is a monoclonal anti-transforming growth factor beta (TGF-beta) antibody that blocks TGF-beta signaling, leading to tumor growth inhibition (PMID: 31692434).

DrugClasses TGFB (Pan) Antibody 5
CAS Registry Number NA
NCIT ID C132250

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Fluorouracil + Irinotecan + Leucovorin + NIS793 Bevacizumab Fluorouracil Irinotecan Leucovorin NIS793 0 1
Bevacizumab + Fluorouracil + Leucovorin + NIS793 + Oxaliplatin Bevacizumab Fluorouracil Leucovorin NIS793 Oxaliplatin 0 1
Fluorouracil + Irinotecan + Leucovorin + NIS793 + Oxaliplatin Fluorouracil Irinotecan Leucovorin NIS793 Oxaliplatin 0 2
Gemcitabine + Nab-paclitaxel + NIS793 Gemcitabine NIS793 Nab-paclitaxel 0 2
Gemcitabine + Nab-paclitaxel + NIS793 + Spartalizumab Gemcitabine NIS793 Nab-paclitaxel Spartalizumab 0 1
NIS793 NIS793 0 2
NIS793 + Sabatolimab NIS793 Sabatolimab 0 1
NIS793 + Spartalizumab NIS793 Spartalizumab 0 1


Additional content available in CKB BOOST