Drug Detail


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Drug Name RXDX-106
Trade Name
Synonyms CEP-40783|CEP40783|CEP 40783|RXDX106|RXDX 106
Drug Descriptions

RXDX-106 (CEP-40783) is a small molecule inhibitor of TAM family kinases (Axl, Mertk, and Tyro3) and Met that promotes anti-tumor immune response, resulting in tumor growth inhibition (Eur J Cancer, Vol 69, Supplement 1, December 2016, Page S31, PMID: 30501104, PMID: 30723115).

DrugClasses AXL Inhibitor 28 MERTK Inhibitor 13 MET Inhibitor 56 TYRO3 Inhibitor 8
CAS Registry Number 1437321-24-8
NCIT ID C150585


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Therapy Name Drugs Efficacy Evidence Clinical Trials
RXDX-106 RXDX-106 0 0
RXDX-106 + unspecified PD-1 antibody RXDX-106 unspecified PD-1 antibody 0 0

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