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|Synonyms||CEP-40783|CEP40783|CEP 40783|RXDX106|RXDX 106|
RXDX-106 (CEP-40783) is a small molecule inhibitor of TAM family kinases (Axl, Mertk, and Tyro3) and Met that promotes anti-tumor immune response, resulting in tumor growth inhibition (Eur J Cancer, Vol 69, Supplement 1, December 2016, Page S31, PMID: 30501104, PMID: 30723115).
|DrugClasses||AXL Inhibitor 28 MERTK Inhibitor 13 MET Inhibitor 56 TYRO3 Inhibitor 8|
|CAS Registry Number||1437321-24-8|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|RXDX-106 + unspecified PD-1 antibody||RXDX-106 unspecified PD-1 antibody||0||0|