Drug Detail


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Drug Name SX-682
Trade Name
Synonyms SX682|SX 682
Drug Descriptions

SX-682 is an inhibitor of the C-X-C chemokine receptor types, CXCR1 and CXCR2, resulting in reduced neutrophil chemotaxis and decreased tumor cell tumor cell migration (PMID: 31848188).

DrugClasses CXCR Antagonist 4
CAS Registry Number 1648843-04-2
NCIT ID C150389


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bintrafusp alfa + CV301 + SX-682 Bintrafusp alfa CV301 SX-682 0 0
Bintrafusp alfa + FPV-CV301 + MVA-BN-CV301 + SX-682 Bintrafusp alfa FPV-CV301 MVA-BN-CV301 SX-682 0 1
Nivolumab + SX-682 Nivolumab SX-682 0 2
Osimertinib + SHP099 + SX-682 Osimertinib SHP099 SX-682 0 0
Pembrolizumab + SX-682 Pembrolizumab SX-682 0 2
SHP099 + SX-682 SHP099 SX-682 0 0
SX-682 SX-682 0 3
SX-682 + Tislelizumab SX-682 Tislelizumab 0 1

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