Drug Detail


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Drug Name Aumolertinib
Trade Name
Synonyms HS-10296||HS10296|Almonertinib
Drug Descriptions

Aumolertinib (HS-10296) is a third-generation small molecule inhibitor of EGFR activating mutations and EGFR T790M (PMID: 28149837, PMID: 32895156).

DrugClasses EGFR Inhibitor 3rd gen 26
CAS Registry Number 1899921-05-1
NCIT ID C133691


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Aumolertinib Afatinib Aumolertinib 0 0
Anlotinib + Aumolertinib + Temozolomide Anlotinib Aumolertinib Temozolomide 0 0
Aumolertinib Aumolertinib 0 2
Aumolertinib + Carboplatin + Gemcitabine Aumolertinib Carboplatin Gemcitabine 0 1
Aumolertinib + Carboplatin + Nab-paclitaxel Aumolertinib Carboplatin Nab-paclitaxel 0 1
Aumolertinib + Carboplatin + Paclitaxel Aumolertinib Carboplatin Paclitaxel 0 1
Aumolertinib + Carboplatin + Pemetrexed Disodium Aumolertinib Carboplatin Pemetrexed Disodium 0 1
Aumolertinib + Cisplatin + Gemcitabine Aumolertinib Cisplatin Gemcitabine 0 1
Aumolertinib + Cisplatin + Nab-paclitaxel Aumolertinib Cisplatin Nab-paclitaxel 0 1
Aumolertinib + Cisplatin + Paclitaxel Aumolertinib Cisplatin Paclitaxel 0 1
Aumolertinib + Cisplatin + Pemetrexed Disodium Aumolertinib Cisplatin Pemetrexed Disodium 0 1
Aumolertinib + Crizotinib Aumolertinib Crizotinib 0 0

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