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Drug Name Asparaginase Erwinia chrysanthemi
Trade Name Erwinaze
Synonyms Crisantaspase
Drug Descriptions

Erwinaze (asparaginase Erwinia chrysanthemi) is an bacterial derived enzyme that converts L-asparagine to L-aspartate and ammonia, which decreases L-asparagine levels, potentially leading to reduced leukemic cell growth (PMID: 25098829, PMID: 26698391). Erwinaze (asparaginase Erwinia chrysanthemi) is FDA-approved for use in a chemotherapeutic regimen for acute lymphoblastic leukemia (FDA.gov).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Asparaginase Erwinia chrysanthemi Asparaginase Erwinia chrysanthemi 0 1
Asparaginase Erwinia chrysanthemi + Cytarabine Asparaginase Erwinia chrysanthemi Cytarabine 0 1
Asparaginase Erwinia chrysanthemi + Cytarabine + Sorafenib Asparaginase Erwinia chrysanthemi Cytarabine Sorafenib 0 1


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