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REGN2878-DM1 is an antibody-drug conjugate comprising an antibody targeting the Prolactin Receptor (PRLR) linked to DM1, which delivers the cytotoxic agent to PRLR-expressing tumor cells, potentially resulting in increased cell-cycle arrest and decreased tumor growth (PMID: 28377489).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Fulvestrant + REGN2878-DM1||Fulvestrant REGN2878-DM1||0||0|