Drug Detail


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Drug Name ASTX-660
Trade Name
Synonyms ASTX660|ASTX 660
Drug Descriptions

ASTX-660 is a SMAC mimetic that inhibits cIAP and XIAP, potentially resulting in tumor cell death (Cancer Res 2016;76(14 Suppl):Abstract nr 1287, PMID: 31900279).

DrugClasses SMAC Mimetic 8
CAS Registry Number 1799328-86-1
NCIT ID C123913


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ASTX-660 ASTX-660 0 2
ASTX-660 + Decitabine and Cedazuridine ASTX-660 Decitabine and Cedazuridine 0 1
ASTX-660 + Paclitaxel ASTX-660 Paclitaxel 0 0
ASTX-660 + Pembrolizumab ASTX-660 Pembrolizumab 0 1

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