Drug Detail


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Drug Name MGD013
Trade Name
Synonyms MGD-013|Tebotelimab
Drug Descriptions

MGD013 is an engineered antibody protein that targets both PDCD1 (PD-1) and LAG3 resulting in enhanced T-cell mediated anti-tumor immune response (Cancer Res July 15 2016 (76) (14 Supplement) 3217).

DrugClasses Immune Checkpoint Inhibitor 147 LAG3 Antibody 17 PD-L1/PD-1 antibody 86
CAS Registry Number NA
NCIT ID C143957


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Capecitabine + Margetuximab-cmkb + MGD013 + Oxaliplatin Capecitabine MGD013 Margetuximab-cmkb Oxaliplatin 0 1
Fluorouracil + Leucovorin + Margetuximab-cmkb + MGD013 + Oxaliplatin Fluorouracil Leucovorin MGD013 Margetuximab-cmkb Oxaliplatin 0 1
Margetuximab-cmkb + MGD013 MGD013 Margetuximab-cmkb 0 0
MGA271 + MGD013 MGA271 MGD013 0 1
MGD013 MGD013 0 1

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