Drug Detail


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Drug Name Silmitasertib
Trade Name
Synonyms CX-4945|CX4945
Drug Descriptions

Silmitasertib (CX-4945) inhibits protein kinase CK2 (CSNK2), potentially resulting in decreased growth of tumor cells, alone and in combination with other agents (PMID: 21159648, PMID: 27758824, PMID: 32615532).



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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cisplatin + Gemcitabine + Silmitasertib Cisplatin Gemcitabine Silmitasertib 1 1
Fostamatinib + Silmitasertib Fostamatinib Silmitasertib 1 0
Ibrutinib + Silmitasertib Ibrutinib Silmitasertib 1 0
JQ1 + Silmitasertib JQ1 Silmitasertib 1 0
Silmitasertib Silmitasertib 1 2

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